medrx0317

info

Source: HL7 - "Request for Intravenous Chemotherapy (inpatient order) - Alemtuzumab - completed with multiple dosageInstruction lines"

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Dosage

[
  {
    "sequence": 1,
    "text": "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
    "additionalInstruction": [
      {
        "text": "Rapidly increase dose until tolerated"
      },
      {
        "text": "Administer on alternate days"
      }
    ],
    "timing": {
      "repeat": {
        "duration": 12,
        "durationUnit": "wk",
        "frequency": 3,
        "period": 1,
        "periodUnit": "wk"
      }
    },
    "route": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "47625008",
          "display": "Intravenous route (qualifier value)"
        }
      ]
    },
    "method": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "422145002",
          "display": "Inject - dosing instruction imperative (qualifier value)"
        }
      ]
    },
    "doseAndRate": [
      {
        "type": {
          "coding": [
            {
              "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code": "ordered",
              "display": "Ordered"
            }
          ]
        },
        "doseQuantity": {
          "value": 3,
          "unit": "mg",
          "system": "http://unitsofmeasure.org",
          "code": "mg"
        }
      }
    ]
  },
  {
    "sequence": 2,
    "text": "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
    "additionalInstruction": [
      {
        "text": "Rapidly increase dose until tolerated"
      },
      {
        "text": "Administer on alternate days"
      }
    ],
    "timing": {
      "repeat": {
        "duration": 12,
        "durationUnit": "wk",
        "frequency": 3,
        "period": 1,
        "periodUnit": "wk"
      }
    },
    "route": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "47625008",
          "display": "Intravenous route (qualifier value)"
        }
      ]
    },
    "method": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "422145002",
          "display": "Inject - dosing instruction imperative (qualifier value)"
        }
      ]
    },
    "doseAndRate": [
      {
        "type": {
          "coding": [
            {
              "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code": "ordered",
              "display": "Ordered"
            }
          ]
        },
        "doseQuantity": {
          "value": 10,
          "unit": "mg",
          "system": "http://unitsofmeasure.org",
          "code": "mg"
        }
      }
    ]
  },
  {
    "sequence": 3,
    "text": "Rapid daily-dose escalation, until tolerated, from 3 mg/d, and then 10 mg/d, to the recommended maintenance dose of 30 mg IV over 120 min, 3 times per wk on alternate days for up to 12 wk",
    "additionalInstruction": [
      {
        "text": "Rapidly increase dose until tolerated"
      },
      {
        "text": "Administer on alternate days"
      }
    ],
    "timing": {
      "repeat": {
        "duration": 12,
        "durationUnit": "wk",
        "frequency": 3,
        "period": 1,
        "periodUnit": "wk"
      }
    },
    "route": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "47625008",
          "display": "Intravenous route (qualifier value)"
        }
      ]
    },
    "method": {
      "coding": [
        {
          "system": "http://snomed.info/sct",
          "code": "422145002",
          "display": "Inject - dosing instruction imperative (qualifier value)"
        }
      ]
    },
    "doseAndRate": [
      {
        "type": {
          "coding": [
            {
              "system": "http://terminology.hl7.org/CodeSystem/dose-rate-type",
              "code": "ordered",
              "display": "Ordered"
            }
          ]
        },
        "doseQuantity": {
          "value": 30,
          "unit": "mg",
          "system": "http://unitsofmeasure.org",
          "code": "mg"
        }
      }
    ]
  }
]